Publications
C.H. Tran, R. Saha, C. Blanco, D. Bagchi, I.A. Chen (2022) Modulation of α-synuclein aggregation in vitro by a DNA aptamer. Biochemistry 61 (17), 1757-1765
E. Janzen, Y. Shen, A. Vázquez-Salazar, Z. Liu, C. Blanco, J. Kenchel, I.A. Chen (2022) Emergent properties as by-products of prebiotic evolution of aminoacylation ribozymes. Nature communications 13 (1), 1-12
N Kanwar*, C Blanco*, IA Chen, B Seelig (2021) PacBio sequencing output increased through uniform and directional fivefold concatenation. Scientific reports 11 (1), 1-13 [Article in GenomeWeb]
C. Blanco, S. Verbanic, B. Seelig and I. A. Chen (2020) EasyDIVER: a pipeline for assembling and counting high throughput sequencing data from in vitro evolution of nucleic acids or peptides. J. Mol. Evol. 88, 477–481
E. Janzen, C. Blanco, H. Peng, J. Kenchel, I.A. Chen (2020) Promiscuous ribozymes and their proposed role in prebiotic evolution. Chem. Rev. 120, 11, 4879–4897
C. Blanco, S. Verbanic, B. Seelig, I.A. Chen (2020) High-throughput sequencing of in vitro selections of mRNA-displayed peptides: data analysis and applications. Phys. Chem. Chem. Phys. 22: 6492-6506. - 2020 [PCCP HOT article!]
C. Blanco and I.A. Chen (2019) Phage therapy administered noninvasively could be effective in thin tubes subject to episodic flow despite washout: a simulation study. Phys. Biol. 16, 5, 054001
C. Blanco, E. Janzen*, A. Pressman*, R. Saha and I.A. Chen (2019) Molecular fitness landscapes from high-coverage sequence profiling. Annual review of biophysics, Vol. 48:1-18
A.D. Pressman, Z. Liu, E. Janzen, C. Blanco, U.F. Müller, G.F. Joyce, R. Pascal and I.A. Chen (2019) Mapping a systematic ribozyme fitness landscape reveals a frustrated evolutionary network for self-aminoacylating RNA. J. Am. Chem. Soc., 141, 15, 6213-6223
D. Hochberg, C. Blanco and M. Stich (2019) Spontaneous mirror symmetry breaking from recycling in enantioselective polymerization. In: Carballido-Landeira J., Escribano B. (eds) Biological Systems: Nonlinear Dynamics Approach. SEMA SIMAI Springer Series, vol 20. Springer, Cham
C. Blanco, M. Bayas, F. Yan and I.A. Chen (2018) Analysis of evolutionarily independent protein-RNA complexes yields a criterion to evaluate the relevance of prebiotic scenarios. Current Biology 28 (4), 526-537. e5 [Article in phys.org]
[Article in sciencedaily]
[Article in The Current]
[Article in the Daily Nexus]
[Dispatch perspective]
C. Blanco and I.A. Chen (2018) Connections Between Mathematical Models of Prebiotic Evolution and Homochirality. In: Menor-Salván C. (eds) Prebiotic chemistry and chemical evolution of nucleic acids. Nucleic Acids and Molecular Biology, vol 35. Springer, Cham
C. Blanco, M. Stich and D. Hochberg (2017) Mechanically induced homochirality in nucleated enantioselective polymerization. J. Phys. Chem B, 121 (5), 942-955
A. Pressman*, C. Blanco*, I.A. Chen (2015) The RNA World as a model system to study the origin of life. Current Biology, 25 (19), R953-R963
C. Blanco, J.M. Ribo and D. Hochberg (2015) Modeling spontaneous chiral symmetry breaking and deracemization phenomena: discrete versus continuum approaches. Phys. Rev. E, 91 (2) 2:022801
J.M. Ribó, C. Blanco, J. Crusats, Z. El-Hachemi, D. Hochberg and A. Moyano (2014) Absolute asymmetric synthesis in enantioselective autocatalytic reaction networks: theoretical games, speculations on chemical evolution and perhaps a synthetic option. Chem. A Eur. J., 20(52):17250–17271
C. Blanco, J. Crusats, Z. El-Hachemi, A. Moyano, S. Veintemillas-Verdaguer, D. Hochberg and J.M. Ribó (2013) The Viedma deracemization of racemic conglomerate mixtures as a paradigm of spontaneous mirror symmetry breaking in aggregation and polymerization. Chem. Phys. Chem, 14 (17), 3982-3993
C. Blanco, J. Crusats, Z. El-Hachemi, A. Moyano, D. Hochberg and J.M. Ribó (2013) Spontaneous emergence of chirality in the limited enantioselectivity model: autocatalityc cycle driven by an external reagent. Chem. Phys. Chem, 14 (11), 2432
J.M. Ribó, J. Crusats, Z. El-Hachemi, A. Moyano, C. Blanco and D. Hochberg (2013) Spontaneous mirror symmetry breaking in the limited enantioselective autocatalysis model: abyssal hydrothermal vents as scenario for the emergence of chirality in prebiotic chemistry. Astrobiology, 13 (2), 132
C. Blanco, J.M. Ribó, J. Crusats, Z. El-Hachemi, A. Moyano and D. Hochberg (2013) Mirror symmetry breaking with limited enantioselective autocatalysis and temperature gradients: a stability survey. Phys. Chem. Chem. Phys., 15 (5), 1546
M. Stich, C. Blanco and D. Hochberg (2013) Chiral and chemical oscillations in a simple dimerization model. Phys. Chem. Chem. Phys., 15 (1), 255
C. Blanco and D. Hochberg (2012) Models for mirror symmetry breaking via β-sheet-controlled copolymerization: (i) mass balance and (ii) probabilistic treatment. J. Phys. Chem. B, 116 (48), 13953
C. Blanco and D. Hochberg (2012) Induced mirror symmetry breaking via template-controlled copolymerization. Chem. Commun., 48 (30), 3659 (special issue: Chirality)
C. Blanco, D. Hochberg (2012) Multi-state transitions and quantum oscillations of optical activity. Phys. Rev. A, 85 (2), 022114
C. Blanco and D. Hochberg (2013) Stochastic mirror symmetry breaking: theoretical models and simulation of experiments. Topics in Current Chemistry, 333, 157 (special issue: Biochirality)
C. Blanco and D. Hochberg (2012) Homochiral oligopeptides by chiral amplification: interpretation of experimental data with a copolymerization model. Phys. Chem. Chem. Phys., 14 (7), 2301
C. Blanco and D. Hochberg (2011) Chiral symmetry breaking via crystallization of the glycine and α-amino acids system: a mathematical model. Phys. Chem. Chem. Phys., 13 (28), 12920
C. Blanco, M. Stich and D. Hochberg (2011) Temporary mirror symmetry breaking and chiral excursions in open and closed systems. Chem. Phys. Lett., 505 (4), 140
C. Blanco and D. Hochberg (2011) Chiral polymerization: symmetry breaking and entropy production in closed systems. Phys. Chem. Chem. Phys., 13 (3), 839 (special issue: Homochirality and the origin of life) [PCCP HOT PAPER!]
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